cation · a human ion-channel atlas release v1.0-354 · 10.0m cells
CATION Cell ATlas of ION channels

Tissues · 295,906 cells

heart

Cells
295,906
Top channel
RYR2
Cell types present
21
Share of atlas cells
3.0%
plate vi-a — top channels

Top ion channels in heart

Ranked mean expression across cell types; bars coloured by each channel's class.

  1. 01 RYR2 Ca²⁺ store 1.105
  2. 02 CACNA1C Voltage-gated Ca²⁺ 0.657
  3. 03 ITPR2 Ca²⁺ store 0.627
  4. 04 CACNA2D1 Voltage-gated Ca²⁺ 0.557
  5. 05 CACNB2 Voltage-gated Ca²⁺ 0.544
  6. 06 CLIC4 Chloride 0.535
  7. 07 TRPM7 TRP 0.492
  8. 08 CLIC1 Chloride 0.467
  9. 09 ANO6 Chloride 0.424
  10. 10 ITPR1 Ca²⁺ store 0.418
  11. 11 SCN7A Voltage-gated Na⁺ 0.391
  12. 12 STIM1 Ca²⁺ store 0.364
  13. 13 MICU2 Voltage-gated K⁺ 0.356
  14. 14 MICU1 Voltage-gated K⁺ 0.354
  15. 15 PKD2 TRP 0.310
plate vi-b — cell types in this tissue

21 cell types

Ranked by total ion-channel expression. Dominant class = the channel class carrying the largest share of this cell type's expression.

Cell typeDominant classTotal channel expression
cardiac muscle myoblast Ca²⁺ store 1.526
smooth muscle myoblast Ca²⁺ store 1.363
neuronal receptor cell Ca²⁺ store 1.291
visceromotor neuron Voltage-gated Na⁺ 1.268
cardiac muscle cell Ca²⁺ store 1.248
mesothelial cell of epicardium Ca²⁺ store 1.165
cardiac neuron Ca²⁺ store 0.955
fibroblast of cardiac tissue Ca²⁺ store 0.952
endocardial cell Ca²⁺ store 0.950
cardiac blood vessel endothelial cell Ca²⁺ store 0.924
cardiac endothelial cell Ca²⁺ store 0.885
epicardial adipocyte Ca²⁺ store 0.805
lymphoid lineage restricted progenitor cell Ca²⁺ store 0.535
leukocyte Ca²⁺ store 0.507
immature innate lymphoid cell Ca²⁺ store 0.459
dermis microvascular lymphatic vessel endothelial cell Gap junction 0.445
ventricular cardiac muscle cell Ca²⁺ store 0.397
cardiac mesenchymal cell Chloride 0.305
CD8-positive, alpha-beta cytotoxic T cell Ca²⁺ store 0.252
fetal cardiomyocyte Ca²⁺ store 0.170
erythrocyte Chloride 0.093