cation · a human ion-channel atlas release v1.0-354 · 10.0m cells
CATION Cell ATlas of ION channels

Tissues · 163,470 cells

kidney

Cells
163,470
Top channel
CLIC1
Cell types present
49
Share of atlas cells
1.6%
plate vi-a — top channels

Top ion channels in kidney

Ranked mean expression across cell types; bars coloured by each channel's class.

  1. 01 CLIC1 Chloride 0.825
  2. 02 ITPR2 Ca²⁺ store 0.543
  3. 03 SMDT1 Voltage-gated K⁺ 0.469
  4. 04 ITPR1 Ca²⁺ store 0.353
  5. 05 TRPM7 TRP 0.343
  6. 06 CLIC4 Chloride 0.339
  7. 07 MICU2 Voltage-gated K⁺ 0.319
  8. 08 MICU1 Voltage-gated K⁺ 0.306
  9. 09 KCNJ16 Voltage-gated K⁺ 0.295
  10. 10 ANO6 Chloride 0.277
  11. 11 MCU Voltage-gated K⁺ 0.267
  12. 12 PKD2 TRP 0.251
  13. 13 TRPM3 TRP 0.242
  14. 14 CLCN3 Chloride 0.237
  15. 15 STIM2 Ca²⁺ store 0.233
plate vi-b — cell types in this tissue

49 cell types

Ranked by total ion-channel expression. Dominant class = the channel class carrying the largest share of this cell type's expression.

Cell typeDominant classTotal channel expression
epithelial cell of early distal convoluted tubule Ca²⁺ store 1.288
kidney distal convoluted tubule epithelial cell Ca²⁺ store 1.266
kidney connecting tubule epithelial cell Ca²⁺ store 1.223
macula densa epithelial cell Ca²⁺ store 1.211
kidney collecting duct principal cell Ca²⁺ store 1.208
kidney connecting tubule principal cell Ca²⁺ store 1.202
kidney loop of Henle thick ascending limb epithelial cell Ca²⁺ store 1.098
renal principal cell Ca²⁺ store 1.087
papillary tips cell Ca²⁺ store 1.074
kidney collecting duct alpha-intercalated cell Ca²⁺ store 1.033
renal interstitial pericyte Ca²⁺ store 1.003
kidney collecting duct intercalated cell Ca²⁺ store 0.973
renal alpha-intercalated cell Ca²⁺ store 0.964
kidney loop of Henle ascending limb epithelial cell Ca²⁺ store 0.955
kidney outer medulla collecting duct intercalated cell Ca²⁺ store 0.909
kidney loop of Henle thin ascending limb epithelial cell Ca²⁺ store 0.906
kidney interstitial fibroblast Ca²⁺ store 0.904
kidney loop of Henle thin descending limb epithelial cell Ca²⁺ store 0.877
kidney proximal convoluted tubule epithelial cell Ca²⁺ store 0.841
renal beta-intercalated cell Ca²⁺ store 0.746
parietal epithelial cell Ca²⁺ store 0.742
kidney capillary endothelial cell Ca²⁺ store 0.694
epithelial cell of proximal tubule segment 3 Ca²⁺ store 0.690
kidney interstitial alternatively activated macrophage Ca²⁺ store 0.671
interstitial cell Ca²⁺ store 0.632
glomerular capillary endothelial cell Ca²⁺ store 0.620
podocyte Ca²⁺ store 0.577
peritubular capillary endothelial cell Ca²⁺ store 0.558
columnar/cuboidal epithelial cell Chloride 0.543
kidney loop of Henle cortical thick ascending limb epithelial ce Ca²⁺ store 0.530
mesangial cell Ca²⁺ store 0.472
plasmacytoid dendritic cell, human Ca²⁺ store 0.422
vasa recta descending limb cell Chloride 0.413
epithelial cell of proximal tubule Ca²⁺ store 0.396
vasa recta ascending limb cell Ca²⁺ store 0.369
glomerular endothelial cell Chloride 0.357
glomerular mesangial cell Chloride 0.331
kidney interstitial cell Chloride 0.277
kidney epithelial cell Chloride 0.269
kidney cell Chloride 0.260
small pre-B-II cell Ca²⁺ store 0.258
renal intercalated cell Ca²⁺ store 0.229
epithelial cell of nephron Chloride 0.224
B-2 B cell Ca²⁺ store 0.216
mesonephric nephron tubule epithelial cell Chloride 0.213
kidney resident macrophage Chloride 0.212
epithelial cell of proximal tubule segment 1 Chloride 0.200
kidney loop of Henle descending limb epithelial cell Chloride 0.188
urothelial cell Chloride 0.182