cation · a human ion-channel atlas release v1.0-354 · 10.0m cells
CATION Cell ATlas of ION channels

Tissues · 386,103 cells

skin

Cells
386,103
Top channel
CLIC1
Cell types present
22
Share of atlas cells
3.9%
plate vi-a — top channels

Top ion channels in skin

Ranked mean expression across cell types; bars coloured by each channel's class.

  1. 01 CLIC1 Chloride 1.235
  2. 02 SMDT1 Voltage-gated K⁺ 0.522
  3. 03 AQP3 Voltage-gated K⁺ 0.285
  4. 04 CLIC4 Chloride 0.230
  5. 05 MCUB Voltage-gated K⁺ 0.215
  6. 06 ITPR2 Ca²⁺ store 0.206
  7. 07 SCN2B Voltage-gated Na⁺ 0.200
  8. 08 MCOLN2 TRP 0.184
  9. 09 MICU2 Voltage-gated K⁺ 0.179
  10. 10 ANO6 Chloride 0.175
  11. 11 STIM2 Ca²⁺ store 0.172
  12. 12 TRPM7 TRP 0.162
  13. 13 ITPR3 Ca²⁺ store 0.160
  14. 14 MICU1 Voltage-gated K⁺ 0.140
  15. 15 ORAI1 Ca²⁺ store 0.138
plate vi-b — cell types in this tissue

22 cell types

Ranked by total ion-channel expression. Dominant class = the channel class carrying the largest share of this cell type's expression.

Cell typeDominant classTotal channel expression
melanocyte of skin Ca²⁺ store 0.893
epithelial cell of sweat gland Ca²⁺ store 0.731
suprabasal keratinocyte Voltage-gated Na⁺ 0.719
epidermal cell Ca²⁺ store 0.542
granular cell of epidermis Chloride 0.538
sebaceous gland cell Ca²⁺ store 0.503
epidermal Langerhans cell Ca²⁺ store 0.468
sebocyte Ca²⁺ store 0.438
Merkel cell Gap junction 0.414
chondrocyte Ca²⁺ store 0.414
helper T cell Ca²⁺ store 0.366
plasmacytoid dendritic cell Ca²⁺ store 0.347
spinous cell of epidermis Ca²⁺ store 0.339
basal cell of epidermis Ca²⁺ store 0.328
hair follicular keratinocyte Gap junction 0.315
CD8-positive, alpha-beta memory T cell, CD45RO-positive Ca²⁺ store 0.311
stem cell of epidermis Chloride 0.292
conventional dendritic cell Ca²⁺ store 0.283
B-1 B cell Ca²⁺ store 0.241
promonocyte Chloride 0.234
granulocyte monocyte progenitor cell Chloride 0.206
Langerhans cell Chloride 0.197