cation · a human ion-channel atlas release v1.0-354 · 10.0m cells
CATION Cell ATlas of ION channels

Tissues · 293,335 cells

airway

Cells
293,335
Top channel
AQP3
Cell types present
20
Share of atlas cells
2.9%
plate vi-a — top channels

Top ion channels in airway

Ranked mean expression across cell types; bars coloured by each channel's class.

  1. 01 AQP3 Voltage-gated K⁺ 0.631
  2. 02 SMDT1 Voltage-gated K⁺ 0.576
  3. 03 AQP5 Voltage-gated K⁺ 0.344
  4. 04 ITPR2 Ca²⁺ store 0.344
  5. 05 CLIC4 Chloride 0.312
  6. 06 STIM2 Ca²⁺ store 0.290
  7. 07 ANO6 Chloride 0.251
  8. 08 MICU2 Voltage-gated K⁺ 0.244
  9. 09 SCNN1A Voltage-gated Na⁺ 0.244
  10. 10 TRPM7 TRP 0.242
  11. 11 MICU1 Voltage-gated K⁺ 0.239
  12. 12 MCU Voltage-gated K⁺ 0.214
  13. 13 CLCN3 Chloride 0.207
  14. 14 CLIC1 Chloride 0.203
  15. 15 STIM1 Ca²⁺ store 0.188
plate vi-b — cell types in this tissue

20 cell types

Ranked by total ion-channel expression. Dominant class = the channel class carrying the largest share of this cell type's expression.

Cell typeDominant classTotal channel expression
alveolar type 1 fibroblast cell Ca²⁺ store 1.112
lung pericyte Ca²⁺ store 0.920
pulmonary alveolar epithelial cell Ca²⁺ store 0.715
pulmonary alveolar type 2 cell Ca²⁺ store 0.676
pulmonary neuroendocrine cell Voltage-gated Na⁺ 0.622
pulmonary alveolar type 1 cell Chloride 0.602
epithelial cell of lower respiratory tract Ca²⁺ store 0.498
alveolar adventitial fibroblast Ca²⁺ store 0.467
pulmonary artery endothelial cell Ca²⁺ store 0.464
multiciliated columnar cell of tracheobronchial tree Ca²⁺ store 0.437
nasal mucosa goblet cell Ca²⁺ store 0.428
tracheobronchial smooth muscle cell Ca²⁺ store 0.424
myofibroblast cell Chloride 0.385
bronchial goblet cell Ca²⁺ store 0.377
respiratory tract hillock cell Ca²⁺ store 0.359
multiciliated epithelial cell Ca²⁺ store 0.357
elicited macrophage Ca²⁺ store 0.310
primary cultured cell Ca²⁺ store 0.280
tracheal goblet cell Chloride 0.247
tracheobronchial goblet cell Ca²⁺ store 0.230