cation · a human ion-channel atlas release v1.0-354 · 10.0m cells
CATION Cell ATlas of ION channels

Tissues · 238,316 cells

lung

Cells
238,316
Top channel
CLIC1
Cell types present
70
Share of atlas cells
2.4%
plate vi-a — top channels

Top ion channels in lung

Ranked mean expression across cell types; bars coloured by each channel's class.

  1. 01 CLIC1 Chloride 0.945
  2. 02 SMDT1 Voltage-gated K⁺ 0.608
  3. 03 AQP3 Voltage-gated K⁺ 0.345
  4. 04 CLIC4 Chloride 0.321
  5. 05 ITPR2 Ca²⁺ store 0.286
  6. 06 STIM2 Ca²⁺ store 0.244
  7. 07 MICU2 Voltage-gated K⁺ 0.242
  8. 08 MICU1 Voltage-gated K⁺ 0.230
  9. 09 ANO6 Chloride 0.229
  10. 10 MCUB Voltage-gated K⁺ 0.220
  11. 11 TRPM7 TRP 0.213
  12. 12 ITPR1 Ca²⁺ store 0.207
  13. 13 STIM1 Ca²⁺ store 0.196
  14. 14 CLCN3 Chloride 0.190
  15. 15 AQP1 Voltage-gated K⁺ 0.175
plate vi-b — cell types in this tissue

70 cell types

Ranked by total ion-channel expression. Dominant class = the channel class carrying the largest share of this cell type's expression.

Cell typeDominant classTotal channel expression
airway submucosal gland duct basal cell Ca²⁺ store 0.829
contractile cell Ca²⁺ store 0.777
ionocyte Voltage-gated Na⁺ 0.772
serous secreting cell of bronchus submucosal gland Ca²⁺ store 0.747
mucus secreting cell of tracheobronchial tree submucosal gland Ca²⁺ store 0.637
bronchial epithelial cell Ca²⁺ store 0.621
lung interstitial macrophage Ca²⁺ store 0.618
lung goblet cell Ca²⁺ store 0.593
lung perichondrial fibroblast Ca²⁺ store 0.589
smooth muscle cell of the pulmonary artery Ca²⁺ store 0.568
secondary crest myofibroblast Ca²⁺ store 0.563
pulmonary ionocyte Chloride 0.562
lung megakaryocyte Ca²⁺ store 0.560
respiratory tract goblet cell Ca²⁺ store 0.544
adventitial cell Ca²⁺ store 0.535
respiratory tract suprabasal cell Ca²⁺ store 0.526
lung multiciliated epithelial cell Ca²⁺ store 0.479
megakaryocyte Ca²⁺ store 0.479
basophil Ca²⁺ store 0.478
brush cell of tracheobronchial tree Ca²⁺ store 0.470
pulmonary interstitial fibroblast Chloride 0.417
airway submucosal gland collecting duct epithelial cell Ca²⁺ store 0.416
bronchus fibroblast of lung Ca²⁺ store 0.402
respiratory tract epithelial cell Chloride 0.392
lung secretory cell Chloride 0.391
neuroendocrine cell of epithelium of lobar bronchus Ca²⁺ store 0.370
lung resident memory CD8-positive, alpha-beta T cell Ca²⁺ store 0.363
vein endothelial cell of respiratory system Ca²⁺ store 0.360
club cell Ca²⁺ store 0.360
serous secreting cell Ca²⁺ store 0.359
bronchial smooth muscle cell Chloride 0.350
B-1b B cell Ca²⁺ store 0.345
mucus secreting cell of bronchus submucosal gland Chloride 0.342
alveolar capillary type 1 endothelial cell Chloride 0.341
early pro-B cell Chloride 0.338
metallothionein-positive alveolar macrophage Ca²⁺ store 0.338
Schwann cell precursor Chloride 0.337
fibroblast of lung Chloride 0.336
CD22-positive, CD38-low small pre-B cell Ca²⁺ store 0.335
lung macrophage Ca²⁺ store 0.332
B-1a B cell Ca²⁺ store 0.332
cycling pulmonary alveolar type 2 cell Ca²⁺ store 0.331
respiratory basal cell Ca²⁺ store 0.326
myeloid dendritic cell, human Ca²⁺ store 0.313
pulmonary capillary endothelial cell Chloride 0.313
bronchiolar smooth muscle cell Ca²⁺ store 0.308
enucleate erythrocyte Ca²⁺ store 0.305
pre-B-I cell Ca²⁺ store 0.303
endothelial cell of respiratory system lymphatic vessel Voltage-gated Na⁺ 0.300
mesothelial cell of pleura Ca²⁺ store 0.300
alveolar capillary type 2 endothelial cell Ca²⁺ store 0.288
fetal pre-type II pulmonary alveolar epithelial cell Ca²⁺ store 0.286
mononuclear leukocyte Chloride 0.280
group 2 innate lymphoid cell Ca²⁺ store 0.271
early lymphoid progenitor Ca²⁺ store 0.262
adventitial fibroblast Ca²⁺ store 0.261
megakaryocyte-erythroid progenitor cell Ca²⁺ store 0.258
fraction A pre-pro B cell Ca²⁺ store 0.257
precursor B cell Ca²⁺ store 0.252
lung resident memory CD4-positive, alpha-beta T cell Ca²⁺ store 0.249
CD4-positive, CD25-positive, alpha-beta regulatory T cell Ca²⁺ store 0.244
central memory CD4-positive, alpha-beta T cell Ca²⁺ store 0.244
large pre-B-II cell Ca²⁺ store 0.225
pro-B cell Ca²⁺ store 0.221
late pro-B cell Ca²⁺ store 0.218
tracheobronchial serous cell Ca²⁺ store 0.212
T-helper 17 cell Ca²⁺ store 0.191
IgG plasma cell Ca²⁺ store 0.164
IgA plasma cell Ca²⁺ store 0.151
reticulocyte Chloride 0.045