cation · a human ion-channel atlas release v1.0-354 · 10.0m cells
CATION Cell ATlas of ION channels

Tissues · 490,814 cells

eye

Cells
490,814
Top channel
KCNMA1
Cell types present
66
Share of atlas cells
4.9%
plate vi-a — top channels

Top ion channels in eye

Ranked mean expression across cell types; bars coloured by each channel's class.

  1. 01 KCNMA1 Voltage-gated K⁺ 0.901
  2. 02 TRPM3 TRP 0.851
  3. 03 CACNB2 Voltage-gated Ca²⁺ 0.822
  4. 04 CACNA2D1 Voltage-gated Ca²⁺ 0.735
  5. 05 GABRB3 Ligand-gated 0.680
  6. 06 GRID2 Ligand-gated 0.655
  7. 07 GRIA4 Ligand-gated 0.610
  8. 08 RYR2 Ca²⁺ store 0.576
  9. 09 CACNA1C Voltage-gated Ca²⁺ 0.561
  10. 10 MICU2 Voltage-gated K⁺ 0.555
  11. 11 TRPM7 TRP 0.531
  12. 12 ITPR2 Ca²⁺ store 0.520
  13. 13 TRPM1 TRP 0.518
  14. 14 HCN1 Hyperpolarization/CNG 0.493
  15. 15 MICU1 Voltage-gated K⁺ 0.477
plate vi-b — cell types in this tissue

66 cell types

Ranked by total ion-channel expression. Dominant class = the channel class carrying the largest share of this cell type's expression.

Cell typeDominant classTotal channel expression
OFF parasol ganglion cell Voltage-gated Ca²⁺ 2.616
ON parasol ganglion cell Voltage-gated Ca²⁺ 2.446
ON midget ganglion cell Ca²⁺ store 2.422
OFF midget ganglion cell Ca²⁺ store 2.371
S cone cell Hyperpolarization/CNG 2.021
GABAergic amacrine cell Voltage-gated Ca²⁺ 1.989
glycinergic amacrine cell Voltage-gated Ca²⁺ 1.974
diffuse bipolar 3a cell Hyperpolarization/CNG 1.957
midget ganglion cell of retina Voltage-gated Ca²⁺ 1.956
diffuse bipolar 3b cell Voltage-gated Ca²⁺ 1.894
diffuse bipolar 4b cell Hyperpolarization/CNG 1.868
retinal cone cell Hyperpolarization/CNG 1.849
diffuse bipolar 4a cell Voltage-gated Ca²⁺ 1.807
diffuse bipolar 4 cell Voltage-gated Ca²⁺ 1.727
retinal rod cell Hyperpolarization/CNG 1.675
retinal ganglion cell Voltage-gated Na⁺ 1.673
smooth muscle cell of sphincter of pupil Ca²⁺ store 1.666
diffuse bipolar 2 cell Voltage-gated Ca²⁺ 1.661
amacrine cell Voltage-gated Ca²⁺ 1.660
diffuse bipolar 5 cell Voltage-gated Ca²⁺ 1.653
invaginating midget bipolar cell Ca²⁺ store 1.652
retinal pigment epithelial cell TRP 1.650
retinal bipolar neuron Voltage-gated Ca²⁺ 1.586
eye photoreceptor cell Hyperpolarization/CNG 1.539
starburst amacrine cell Voltage-gated Ca²⁺ 1.539
ON-blue cone bipolar cell Voltage-gated Ca²⁺ 1.523
giant bipolar cell Ca²⁺ store 1.497
flat midget bipolar cell Ligand-gated 1.472
rod bipolar cell Ca²⁺ store 1.446
pigmented epithelial cell Ca²⁺ store 1.412
H1 horizontal cell Voltage-gated Ca²⁺ 1.397
diffuse bipolar 1 cell Ligand-gated 1.393
diffuse bipolar 6 cell Voltage-gated Ca²⁺ 1.381
OFFx cell Ligand-gated 1.337
ciliary muscle cell Ca²⁺ store 1.290
pigmented ciliary epithelial cell Ca²⁺ store 1.290
H2 horizontal cell Voltage-gated Ca²⁺ 1.259
ganglion interneuron Voltage-gated Ca²⁺ 1.251
corneal epithelial cell Ca²⁺ store 1.194
non-pigmented ciliary epithelial cell Voltage-gated Ca²⁺ 1.181
lens epithelial cell Ca²⁺ store 1.048
secondary lens fiber Ca²⁺ store 1.046
anterior lens cell Ca²⁺ store 0.966
corneal endothelial cell Ca²⁺ store 0.917
Mueller cell TRP 0.881
retina horizontal cell Voltage-gated Ca²⁺ 0.833
bipolar neuron Ligand-gated 0.831
retinal astrocyte Ca²⁺ store 0.830
retinal blood vessel endothelial cell Ca²⁺ store 0.780
fenestrated endothelial cell Ca²⁺ store 0.737
photoreceptor cell Voltage-gated Ca²⁺ 0.736
lens fiber cell Chloride 0.711
non-myelinating Schwann cell Voltage-gated Na⁺ 0.673
OFF-bipolar cell Ligand-gated 0.631
conjunctival epithelial cell Ca²⁺ store 0.620
retinal progenitor cell TRP 0.610
cone retinal bipolar cell Ligand-gated 0.608
trabecular meshwork cell Ca²⁺ store 0.605
ON-bipolar cell TRP 0.594
melanocyte Ca²⁺ store 0.585
myelinating Schwann cell Chloride 0.557
keratocyte Ca²⁺ store 0.499
basal cell Ca²⁺ store 0.475
goblet cell Ca²⁺ store 0.402
transit amplifying cell Ca²⁺ store 0.364
myeloid leukocyte Ca²⁺ store 0.350