cation · a human ion-channel atlas release v1.0-354 · 10.0m cells
CATION Cell ATlas of ION channels

Tissues · 100,000 cells

midbrain

Cells
100,000
Top channel
GRID2
Cell types present
4
Share of atlas cells
1.0%
plate vi-a — top channels

Top ion channels in midbrain

Ranked mean expression across cell types; bars coloured by each channel's class.

  1. 01 GRID2 Ligand-gated 0.932
  2. 02 ITPR2 Ca²⁺ store 0.848
  3. 03 CACNA2D1 Voltage-gated Ca²⁺ 0.810
  4. 04 GRIK2 Ligand-gated 0.696
  5. 05 CACNA1C Voltage-gated Ca²⁺ 0.594
  6. 06 GRIA2 Ligand-gated 0.566
  7. 07 KCNT2 Voltage-gated K⁺ 0.564
  8. 08 KCNQ3 Voltage-gated K⁺ 0.548
  9. 09 GRIA4 Ligand-gated 0.541
  10. 10 KCNMA1 Voltage-gated K⁺ 0.524
  11. 11 CLIC4 Chloride 0.518
  12. 12 KCND2 Voltage-gated K⁺ 0.498
  13. 13 KCNH7 Voltage-gated K⁺ 0.496
  14. 14 PKD2 TRP 0.488
  15. 15 SCN3A Voltage-gated Na⁺ 0.488
plate vi-b — cell types in this tissue

4 cell types

Ranked by total ion-channel expression. Dominant class = the channel class carrying the largest share of this cell type's expression.

Cell typeDominant classTotal channel expression
dopaminergic neuron Voltage-gated Na⁺ 2.417
midbrain dopaminergic neuron Voltage-gated Ca²⁺ 1.185
cerebral cortex pyramidal neuron Voltage-gated Ca²⁺ 0.754
mesenchymal cell Ca²⁺ store 0.354