cation · a human ion-channel atlas release v1.0-354 · 10.0m cells
CATION Cell ATlas of ION channels

Tissues · 242,400 cells

liver

Cells
242,400
Top channel
CLIC1
Cell types present
28
Share of atlas cells
2.4%
plate vi-a — top channels

Top ion channels in liver

Ranked mean expression across cell types; bars coloured by each channel's class.

  1. 01 CLIC1 Chloride 1.291
  2. 02 SMDT1 Voltage-gated K⁺ 0.664
  3. 03 ITPR2 Ca²⁺ store 0.297
  4. 04 MICU2 Voltage-gated K⁺ 0.231
  5. 05 MICU1 Voltage-gated K⁺ 0.217
  6. 06 TRPM7 TRP 0.216
  7. 07 MCUB Voltage-gated K⁺ 0.211
  8. 08 STIM2 Ca²⁺ store 0.205
  9. 09 CLIC4 Chloride 0.202
  10. 10 STIM1 Ca²⁺ store 0.186
  11. 11 ORAI1 Ca²⁺ store 0.185
  12. 12 ANO6 Chloride 0.181
  13. 13 AQP3 Voltage-gated K⁺ 0.167
  14. 14 CLCN3 Chloride 0.164
  15. 15 ITPR1 Ca²⁺ store 0.162
plate vi-b — cell types in this tissue

28 cell types

Ranked by total ion-channel expression. Dominant class = the channel class carrying the largest share of this cell type's expression.

Cell typeDominant classTotal channel expression
hepatocyte Ca²⁺ store 0.643
cholangiocyte Ca²⁺ store 0.620
centrilobular region hepatocyte Ca²⁺ store 0.596
midzonal region hepatocyte Ca²⁺ store 0.558
periportal region hepatocyte Ca²⁺ store 0.468
hepatic stellate cell Ca²⁺ store 0.466
endothelial cell of pericentral hepatic sinusoid Ca²⁺ store 0.452
intrahepatic cholangiocyte Chloride 0.434
endothelial cell of hepatic sinusoid Ca²⁺ store 0.417
endothelial cell of periportal hepatic sinusoid Ca²⁺ store 0.361
hepatoblast Ca²⁺ store 0.359
Kupffer cell Ca²⁺ store 0.339
malignant cell Ca²⁺ store 0.331
CD16-positive, CD56-dim natural killer cell, human Ca²⁺ store 0.301
hematopoietic stem cell Ca²⁺ store 0.292
common lymphoid progenitor Ca²⁺ store 0.289
cycling myeloid cell Ca²⁺ store 0.289
common dendritic progenitor Ca²⁺ store 0.268
gamma-delta T cell Ca²⁺ store 0.250
inflammatory macrophage Ca²⁺ store 0.248
hematopoietic multipotent progenitor cell Ca²⁺ store 0.232
CD8-positive, alpha-beta memory T cell Ca²⁺ store 0.229
CD4-positive, alpha-beta memory T cell Ca²⁺ store 0.224
cycling plasma cell Chloride 0.221
effector memory CD8-positive, alpha-beta T cell Ca²⁺ store 0.221
liver dendritic cell Chloride 0.200
hepatic pit cell Ca²⁺ store 0.187
proerythroblast Ca²⁺ store 0.165